Posts tagged THC LD50
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You know there is quite a bit of controversy surrounding the topic of marijuana overdose, despite there having been no reported cases ever. Frankly, we just don’t think its possible and neither do 9 out of our 10 visitors. It might be possible that someone with an allergy to marijuana could die from ingesting it, however due to its legal status in many places there has been little research conducted on a marijuana allergy. It is a plant, some people are allergic to certain plants, it only makes sense that certain people would be allergic to marijuana. And of course, everyone has heard the old urban legend, “You can overdose on weed if you smoke your weight.” The Merck Index lists the LD50 (dosage of a certain chemical which will kill half of a population given that dosage) of pure THC to be 42 mg per kg of body weight for rats when the THC is inhaled. What does this mean for us? The lesson I learned is, if you have pure THC, please, don’t waste it getting rats high.
Now, let’s make some assumptions with this Merck Index LD50 of 42mg/kg. So, let’s assume we have a 75kg person (165 lbs) and that this LD50 also applies to humans, that gives us 3150 mg or 3.15 g. But, even hash oil isn’t pure THC, neither is hash, nor is weed itself. Assuming that you have the best hash oil in the world and it is 90% pure, you would need to smoke 3.5 grams in order to have a 50% chance of dying. Assuming you have some awesome hash and it is 70% pure, you would need to smoke 4.5 grams in order to have a 50% chance of dying. And lastly, assuming you have some top shelf weed from a dispensary and it has a 20% purity, you would need to smoke 15.75 grams in order to give yourself a 50% chance of dying.
Personally, I’ll stick with these numbers and assume that they are correct and that all the assumptions are correct. I still think it is impossible to overdose on marijuana, because 99.9% of people (in my opinion) would be fast asleep before smoking 3.5 grams of hash oil, 4.5 grams of hash, or 15.75 grams of pot. Anyone who could smoke more than these amounts has likely built up a tolerance to THC ala Johnny Depp in his roles as George Jung in the movie Blow.
So, where does this leave us. Well let’s start with the basics, it’s impossible to overdose on marijuana. But, if you could effectively smoke your body weight in a short period of time without falling asleep you maybe will die. Seeing as you can’t, there’s really nothing to worry about unless you are allergic. Of course if you are allergic to marijuana, you are probably allergic to the pollen and would be perfectly fine inhaling marijuana smoke. But, that’s enough of what we have to say. Vote in our poll, and feel free to posts any comments or questions you may have. If you are going to attempt to smoke your weight in marijuana, please contact us directly at firstname.lastname@example.org as we would like to help document, administer, and participate in your experiment.